Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation

AIM: Ursolic acid (UA) is a pentacyclic triterpenoid found in most plant species, which has been shown anti-inflammatory and anti-oxidative activities. In this study, we examined the effects of UA on collagen-induced arthritis (CIA) in mice, and to identify the mechanisms underlying the effects. MET...

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Detalhes bibliográficos
Main Authors: Baek, Seung-ye, Lee, Jaeseon, Lee, Dong-gun, Park, Mi-kyung, Lee, Jennifer, Kwok, Seung-ki, Cho, Mi-la, Park, Sung-hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155530/
https://ncbi.nlm.nih.gov/pubmed/25087995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.58
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