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Mixed Model Association with Family-Biased Case-Control Ascertainment
Mixed models have become the tool of choice for genetic association studies; however, standard mixed model methods may be poorly calibrated or underpowered under family sampling bias and/or case-control ascertainment. Previously, we introduced a liability threshold-based mixed model association stat...
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| Publicat a: | Am J Hum Genet |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223022/ https://ncbi.nlm.nih.gov/pubmed/28017371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.11.015 |
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