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Mixed Model Association with Family-Biased Case-Control Ascertainment

Mixed models have become the tool of choice for genetic association studies; however, standard mixed model methods may be poorly calibrated or underpowered under family sampling bias and/or case-control ascertainment. Previously, we introduced a liability threshold-based mixed model association stat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Hum Genet
Prif Awduron: Hayeck, Tristan J., Loh, Po-Ru, Pollack, Samuela, Gusev, Alexander, Patterson, Nick, Zaitlen, Noah A., Price, Alkes L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223022/
https://ncbi.nlm.nih.gov/pubmed/28017371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.11.015
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