C-C Motif Chemokine 5 Attenuates Angiotensin II–Dependent Kidney Injury by Limiting Renal Macrophage Infiltration

Inappropriate activation of the renin angiotensin system (RAS) is a key contributor to the pathogenesis of essential hypertension. During RAS activation, infiltration of immune cells into the kidney exacerbates hypertension and renal injury. However, the mechanisms underpinning the accumulation of m...

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Udgivet i:Am J Pathol
Main Authors: Rudemiller, Nathan P., Patel, Mehul B., Zhang, Jian-dong, Jeffs, Alexander D., Karlovich, Norah S., Griffiths, Robert, Kan, Matthew J., Buckley, Anne F., Gunn, Michael D., Crowley, Steven D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2016
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222967/
https://ncbi.nlm.nih.gov/pubmed/27640148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.07.015
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