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A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

The complexity of the tumor microenvironment is difficult to mimic in vitro, particularly regarding tumor–host interactions. To enable better assessment of cancer immunotherapy agents in vitro, we developed a three-dimensional (3D) heterotypic spheroid model composed of tumor cells, fibroblasts, and...

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Publicat a:Cancer Immunol Immunother
Autors principals: Herter, Sylvia, Morra, Laura, Schlenker, Ramona, Sulcova, Jitka, Fahrni, Linda, Waldhauer, Inja, Lehmann, Steffi, Reisländer, Timo, Agarkova, Irina, Kelm, Jens M., Klein, Christian, Umana, Pablo, Bacac, Marina
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222939/
https://ncbi.nlm.nih.gov/pubmed/27858101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1927-1
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