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A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents
The complexity of the tumor microenvironment is difficult to mimic in vitro, particularly regarding tumor–host interactions. To enable better assessment of cancer immunotherapy agents in vitro, we developed a three-dimensional (3D) heterotypic spheroid model composed of tumor cells, fibroblasts, and...
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| Publicat a: | Cancer Immunol Immunother |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222939/ https://ncbi.nlm.nih.gov/pubmed/27858101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1927-1 |
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