Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

High-grade serous ovarian cancer (HGSOC) is hallmarked by early onset of peritoneal dissemination, which distinguishes it from low-grade serous ovarian cancer (LGSOC). Here, we describe the aggressive nature of HGSOC ascitic tumor cells (ATCs) characterized by integrin α5(high) (ITGA5(high)) ATCs, w...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Gao, Qinglei, Yang, Zongyuan, Xu, Sen, Li, Xiaoting, Yang, Xin, Jin, Ping, Liu, Yi, Zhou, Xiaoshui, Zhang, Taoran, Gong, Cheng, Wei, Xiao, Liu, Dan, Sun, Chaoyang, Chen, Gang, Hu, Junbo, Meng, Li, Zhou, Jianfeng, Sawada, Kenjiro, Fruscio, Robert, Grunt, Thomas W., Wischhusen, Jörg, Vargas-Hernández, Víctor Manuel, Pothuri, Bhavana, Coleman, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400537/
https://ncbi.nlm.nih.gov/pubmed/30710055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180765
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