Differential Cultivation of Francisella tularensis Induces Changes in the Immune Response to and Protective Efficacy of Whole Cell-Based Inactivated Vaccines

Francisella tularensis (Ft) is a category A biothreat agent for which there is no Food and Drug Administration-approved vaccine. Ft can survive in a variety of habitats with a remarkable ability to adapt to changing environmental conditions. Furthermore, Ft expresses distinct sets of antigens (Ags)...

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Udgivet i:Front Immunol
Main Authors: Kumar, Sudeep, Sunagar, Raju, Pham, Giang, Franz, Brian J., Rosa, Sarah J., Hazlett, Karsten R. O., Gosselin, Edmund J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222797/
https://ncbi.nlm.nih.gov/pubmed/28119692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00677
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