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Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immunization has the potential to downmodulate immune prote...

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Publicat a:J Immunol Res
Autors principals: Franz, Brian J., Li, Ying, Bitsaktsis, Constantine, Iglesias, Bibiana V., Pham, Giang, Sunagar, Raju, Kumar, Sudeep, Gosselin, Edmund J.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417568/
https://ncbi.nlm.nih.gov/pubmed/25961064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/840842
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