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Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immunization has the potential to downmodulate immune prote...

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Библиографические подробности
Опубликовано в: :J Immunol Res
Главные авторы: Franz, Brian J., Li, Ying, Bitsaktsis, Constantine, Iglesias, Bibiana V., Pham, Giang, Sunagar, Raju, Kumar, Sudeep, Gosselin, Edmund J.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417568/
https://ncbi.nlm.nih.gov/pubmed/25961064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/840842
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