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Targeting of a Fixed Bacterial Immunogen to Fc Receptors Reverses the Anti-Inflammatory Properties of the Gram-Negative Bacterium, Francisella tularensis, during the Early Stages of Infection

Production of pro-inflammatory cytokines by innate immune cells at the early stages of bacterial infection is important for host protection against the pathogen. Many intracellular bacteria, including Francisella tularensis, the agent of tularemia, utilize the anti-inflammatory cytokine IL-10, to ev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Babadjanova, Zulfia, Wiedinger, Kari, Gosselin, Edmund J., Bitsaktsis, Constantine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482730/
https://ncbi.nlm.nih.gov/pubmed/26114641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129981
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