Differential In Vitro Cultivation of Francisella tularensis Influences Live Vaccine Protective Efficacy by Altering the Immune Response

Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and improved tools to assess these vaccines. Ft expresses distinct sets of antigens (Ags) in vivo as compared to those express...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sunagar, Raju, Kumar, Sudeep, Rosa, Sarah J., Hazlett, Karsten R. O., Gosselin, Edmund J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048226/
https://ncbi.nlm.nih.gov/pubmed/30042767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01594
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