68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment

Leucine-rich repeat kinase 2 is a large protein with implications in genetic and sporadic causes of Parkinson's disease. The physiological functions of LRRK2 are largely unknown. In this report, we investigated whether LRRK2 alters neural transport using live-cell imaging techniques and human n...

Full description

Saved in:
Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Thomas, Joseph M., Li, Tianxia, Yang, Wei, Xue, Fengtian, Fishman, Paul S., Smith, Wanli W.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222795/
https://ncbi.nlm.nih.gov/pubmed/28119604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00337
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items