Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences

Repair of chromosomal breaks is essential for cellular viability, but misrepair generates mutations and gross chromosomal rearrangements. We investigated the interrelationship between two homologous-repair pathways, i.e., mutagenic single-strand annealing (SSA) and precise homology-directed repair (...

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Detalhes bibliográficos
Main Authors: Stark, Jeremy M., Pierce, Andrew J., Oh, Jin, Pastink, Albert, Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522275/
https://ncbi.nlm.nih.gov/pubmed/15485900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9305-9316.2004
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