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Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase

DNA repair by homologous recombination (HR) underpins cell survival and fuels genome instability, cancer, and evolution. However, the main kinds and sources of DNA damage repaired by HR in somatic cells and the roles of important HR proteins remain elusive. We present engineered proteins that trap,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: Xia, Jun, Chen, Li-Tzu, Mei, Qian, Ma, Chien-Hui, Halliday, Jennifer A., Lin, Hsin-Yu, Magnan, David, Pribis, John P., Fitzgerald, Devon M., Hamilton, Holly M., Richters, Megan, Nehring, Ralf B., Shen, Xi, Li, Lei, Bates, David, Hastings, P. J., Herman, Christophe, Jayaram, Makkuni, Rosenberg, Susan M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222578/
https://ncbi.nlm.nih.gov/pubmed/28090586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601605
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