Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase

DNA repair by homologous recombination (HR) underpins cell survival and fuels genome instability, cancer, and evolution. However, the main kinds and sources of DNA damage repaired by HR in somatic cells and the roles of important HR proteins remain elusive. We present engineered proteins that trap,...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Xia, Jun, Chen, Li-Tzu, Mei, Qian, Ma, Chien-Hui, Halliday, Jennifer A., Lin, Hsin-Yu, Magnan, David, Pribis, John P., Fitzgerald, Devon M., Hamilton, Holly M., Richters, Megan, Nehring, Ralf B., Shen, Xi, Li, Lei, Bates, David, Hastings, P. J., Herman, Christophe, Jayaram, Makkuni, Rosenberg, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222578/
https://ncbi.nlm.nih.gov/pubmed/28090586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601605
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