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The C-terminal acidic region of calreticulin mediates phosphatidylserine binding and apoptotic cell phagocytosis
Calreticulin is a calcium-binding chaperone that is normally localized in the endoplasmic reticulum (ER). Calreticulin is detectable on the surface of apoptotic cell under some apoptosis-inducing conditions, where it promotes phagocytosis and immunogenicity of dying cells. However, the precise mecha...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222549/ https://ncbi.nlm.nih.gov/pubmed/27036911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502122 |
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