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A calreticulin tail: C-terminal mutants of calreticulin allow cancer cells to evade phagocytosis

In the current issue of Molecular cell, Liu et al. (2020) show that the secretion of cancer-linked forms of mutant calreticulin allow cancer cells to escape protective immune responses induced by chemotherapeutic and immunotherapeutic drugs, thereby promoting tumor growth.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Kaur, Amanpreet, Raghavan, Malini
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594649/
https://ncbi.nlm.nih.gov/pubmed/32084350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.024
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