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The C-terminal acidic region of calreticulin mediates phosphatidylserine binding and apoptotic cell phagocytosis

Calreticulin is a calcium-binding chaperone that is normally localized in the endoplasmic reticulum (ER). Calreticulin is detectable on the surface of apoptotic cell under some apoptosis-inducing conditions, where it promotes phagocytosis and immunogenicity of dying cells. However, the precise mecha...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Wijeyesakere, Sanjeeva Joseph, Bedi, Sukhmani Kaur, Huynh, David, Raghavan, Malini
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222549/
https://ncbi.nlm.nih.gov/pubmed/27036911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502122
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