In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Hypoxia has been implicated in the metastasis of Ewing sarcoma (ES) by clinical observations and in vitro data, yet direct evidence for its pro-metastatic effect is lacking and the exact mechanisms of its action are unclear. Here, we report an animal model that allows for direct testing of the effec...

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Veröffentlicht in:J Vis Exp
Hauptverfasser: Hong, Sung-Hyeok, Tilan, Jason U., Galli, Susana, Acree, Rachel, Connors, Katherine, Mahajan, Akanksha, Wietlisbach, Larissa, Polk, Taylor, Izycka-Swieszewska, Ewa, Lee, Yi-Chien, Cavalli, Luciane R., Rodriguez, Olga C., Albanese, Chris, Kitlinska, Joanna B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2016
Schlagworte:
Cancer Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222526/
https://ncbi.nlm.nih.gov/pubmed/28060251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54532
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