In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Hypoxia has been implicated in the metastasis of Ewing sarcoma (ES) by clinical observations and in vitro data, yet direct evidence for its pro-metastatic effect is lacking and the exact mechanisms of its action are unclear. Here, we report an animal model that allows for direct testing of the effec...

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發表在:J Vis Exp
Main Authors: Hong, Sung-Hyeok, Tilan, Jason U., Galli, Susana, Acree, Rachel, Connors, Katherine, Mahajan, Akanksha, Wietlisbach, Larissa, Polk, Taylor, Izycka-Swieszewska, Ewa, Lee, Yi-Chien, Cavalli, Luciane R., Rodriguez, Olga C., Albanese, Chris, Kitlinska, Joanna B.
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2016
主題:
Cancer Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222526/
https://ncbi.nlm.nih.gov/pubmed/28060251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54532
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