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In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Hypoxia has been implicated in the metastasis of Ewing sarcoma (ES) by clinical observations and in vitro data, yet direct evidence for its pro-metastatic effect is lacking and the exact mechanisms of its action are unclear. Here, we report an animal model that allows for direct testing of the effec...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Hong, Sung-Hyeok, Tilan, Jason U., Galli, Susana, Acree, Rachel, Connors, Katherine, Mahajan, Akanksha, Wietlisbach, Larissa, Polk, Taylor, Izycka-Swieszewska, Ewa, Lee, Yi-Chien, Cavalli, Luciane R., Rodriguez, Olga C., Albanese, Chris, Kitlinska, Joanna B.
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222526/
https://ncbi.nlm.nih.gov/pubmed/28060251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54532
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