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Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer
Structural rearrangements of HIV-1 glycoprotein Env promote viral entry through membrane fusion. Env is a symmetric homotrimer with each protomer composed of surface subunit gp120 and transmembrane subunit gp41. Cellular CD4- and chemokine receptor-binding to gp120 coordinate conformational changes...
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| Vydáno v: | PLoS Pathog |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222517/ https://ncbi.nlm.nih.gov/pubmed/27992602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006098 |
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