Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice

Poly(ADP-ribosyl)ation is rapidly formed in cells following DNA damage and is regulated by poly(ADP-ribose) polymerase-1 (PARP-1). PARP-1 is known to be involved in various cellular processes, such as DNA repair, genomic stability, transcription, and cell death. During apoptosis, PARP-1 is cleaved b...

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Autors principals: Pétrilli, Virginie, Herceg, Zdenko, Hassa, Paul O., Patel, Nimesh S.A., Di Paola, Rosanna, Cortes, Ulrich, Dugo, Laura, Filipe, Helder-Mota, Thiemermann, Christoph, Hottiger, Michael O., Cuzzocrea, Salvatore, Wang, Zhao-Qi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC522248/
https://ncbi.nlm.nih.gov/pubmed/15489954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421854
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