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BRUCE, a Giant E2/E3 Ubiquitin Ligase and Inhibitor of Apoptosis Protein of the trans-Golgi Network, Is Required for Normal Placenta Development and Mouse Survival

BRUCE is a highly conserved 528-kDa peripheral membrane protein of the trans-Golgi network. Owing to the presence of an N-terminal single baculovirus inhibitor repeat, BRUCE functions as an inhibitor of apoptosis protein and blocks apoptosis when overexpressed. In addition, due to the presence of a...

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Hlavní autoři: Lotz, Kristina, Pyrowolakis, George, Jentsch, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC522247/
https://ncbi.nlm.nih.gov/pubmed/15485903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9339-9350.2004
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