The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production

HIV type 1 (HIV-1) was shown to assemble either at the plasma membrane or in the membrane of late endosomes. Now, we report an essential role for human ubiquitin ligase POSH (Plenty of SH3s; hPOSH), a trans-Golgi network-associated protein, in the targeting of HIV-1 to the plasma membrane. Small inh...

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Detalles Bibliográficos
Main Authors: Alroy, Iris, Tuvia, Shmuel, Greener, Tsvika, Gordon, Daphna, Barr, Haim M., Taglicht, Daniel, Mandil-Levin, Revital, Ben-Avraham, Danny, Konforty, Dalit, Nir, Anat, Levius, Orit, Bicoviski, Vivian, Dori, Mally, Cohen, Shenhav, Yaar, Liora, Erez, Omri, Propheta-Meiran, Oshrat, Koskas, Mordechai, Caspi-Bachar, Elanite, Alchanati, Iris, Sela-Brown, Alin, Moskowitz, Haim, Tessmer, Uwe, Schubert, Ulrich, Reiss, Yuval
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC545085/
https://ncbi.nlm.nih.gov/pubmed/15659549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408717102
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