Cell-Surface Integrins and CAR Are Both Essential for Adenovirus Type 5 Transduction of Canine Cells of Lymphocytic Origin

Adenoviruses are the most widely used vectors in cancer gene therapy. Adenoviruses vectors are well characterized and are easily manipulated. Adenovirus serotype 5 (Ad5) is the most commonly used human serotype. Ad5 internalization into host cells is a combined effect of binding of Ad5 fiber knob wi...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Agarwal, Payal, Gammon, Elizabeth A., Sajib, Abdul Mohin, Sandey, Maninder, Smith, Bruce F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222425/
https://ncbi.nlm.nih.gov/pubmed/28068367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169532
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