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Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: The coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction.
Understanding virus-cell interaction is a key to the design of successful gene delivery vectors. In the present study we investigated Ad5 transduction of enterocytes and M-cells utilizing differentiated Caco-2 cells and co-cultures of Caco-2 cells with lymphocytes. Transduction inhibition studies sh...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882510/ https://ncbi.nlm.nih.gov/pubmed/20235596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp9001377 |
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