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Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: The coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction.

Understanding virus-cell interaction is a key to the design of successful gene delivery vectors. In the present study we investigated Ad5 transduction of enterocytes and M-cells utilizing differentiated Caco-2 cells and co-cultures of Caco-2 cells with lymphocytes. Transduction inhibition studies sh...

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Detaylı Bibliyografya
Asıl Yazarlar: Kesisoglou, Filippos, Schmiedlin-Ren, Phyllissa, Fleisher, David, Zimmermann, Ellen M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882510/
https://ncbi.nlm.nih.gov/pubmed/20235596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp9001377
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