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Accessibility of the coxsackievirus and adenovirus receptor and its importance in adenovirus gene transduction efficiency

Viruses are commonly investigated as vector systems for gene therapy. To be effective, virus-mediated gene-delivery systems require the presence of specific virus receptors to enter the target cell. One example is adenovirus and its primary receptor is the coxsackievirus and adenovirus receptor (CAR...

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Detalhes bibliográficos
Main Authors: Sharma, Priyanka, Kolawole, Abimbola Olayinka, Wiltshire, Sydney Marie, Frondorf, Kathleen, Excoffon, Katherine Julie Diane Ashbourne
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352330/
https://ncbi.nlm.nih.gov/pubmed/21918008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.036269-0
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