Analysis of endogenous and exogenous tumor upregulated promoter expression in canine tumors

Gene therapy is a promising treatment option for cancer. However, its utility may be limited due to expression in off-target cells. Cancer-specific promoters such as telomerase reverse transcriptase (TERT), survivin, and chemokine receptor 4 (CXCR4) have enhanced activity in a variety of human and m...

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Vydáno v:PLoS One
Hlavní autoři: Sajib, Abdul Mohin, Sandey, Maninder, Morici, Samantha, Schuler, Bradley, Agarwal, Payal, Smith, Bruce F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652315/
https://ncbi.nlm.nih.gov/pubmed/33166332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240807
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