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Tumor Necrosis Factor Alpha Induction of NF-κB Requires the Novel Coactivator SIMPL
A myriad of stimuli including proinflammatory cytokines, viruses, and chemical and mechanical insults activate a kinase complex composed of IκB kinase β (IKK-β), IKK-α, and IKK-γ/N, leading to changes in NF-κB-dependent gene expression. However, it is not clear how the NF-κB response is tailored to...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522234/ https://ncbi.nlm.nih.gov/pubmed/15485901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9317-9326.2004 |
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