Φορτώνει......
Central Role of the Threonine Residue within the p+1 Loop of Receptor Tyrosine Kinase in STAT3 Constitutive Phosphorylation in Metastatic Cancer Cells
The receptor tyrosine kinases (RTKs) RET, MET, and RON all carry the Met(p+1loop)→Thr point mutation (i.e., 2B mutation), leading to the formation of tumors with high metastatic potential. Utilizing a novel antibody array, we identified constitutive phosphorylation of STAT3 in cells expressing the 2...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522220/ https://ncbi.nlm.nih.gov/pubmed/15485908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9390-9400.2004 |
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