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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans

The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and guidance cues with their respective receptors to elicit appropriate cellular responses. Heparan sulfate proteoglycans consist of a protein core w...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Blanchette, Cassandra R., Thackeray, Andrea, Perrat, Paola N., Hekimi, Siegfried, Bénard, Claire Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221758/
https://ncbi.nlm.nih.gov/pubmed/28068429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006525
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