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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans

The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and guidance cues with their respective receptors to elicit appropriate cellular responses. Heparan sulfate proteoglycans consist of a protein core w...

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Foilsithe in:PLoS Genet
Main Authors: Blanchette, Cassandra R., Thackeray, Andrea, Perrat, Paola N., Hekimi, Siegfried, Bénard, Claire Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221758/
https://ncbi.nlm.nih.gov/pubmed/28068429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006525
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