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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans

The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and guidance cues with their respective receptors to elicit appropriate cellular responses. Heparan sulfate proteoglycans consist of a protein core w...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Autores principales: Blanchette, Cassandra R., Thackeray, Andrea, Perrat, Paola N., Hekimi, Siegfried, Bénard, Claire Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221758/
https://ncbi.nlm.nih.gov/pubmed/28068429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006525
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