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The pleckstrin-homology domain of dynamin is dispensable for membrane constriction and fission

Classical dynamins bind the plasma membrane–localized phosphatidylinositol-4,5-bisphosphate using the pleckstrin-homology domain (PHD) and engage in rapid membrane fission during synaptic vesicle recycling. This domain is conspicuously absent among extant bacterial and mitochondrial dynamins, howeve...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Dar, Srishti, Pucadyil, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221619/
https://ncbi.nlm.nih.gov/pubmed/28035046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0640
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