Cocaine-mediated downregulation of microglial miR-124 expression involves promoter DNA methylation

Neuroinflammation plays a critical role in the development of reward-related behavior in cocaine self-administration rodents. Cocaine, one of most commonly abused drugs, has been shown to activate microglia both in vitro and in vivo. Detailed molecular mechanisms underlying cocaine-mediated microgli...

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Foilsithe in:Epigenetics
Main Authors: Guo, Ming-Lei, Periyasamy, Palsamy, Liao, Ke, Kook, Yeon Hee, Niu, Fang, Callen, Shannon E., Buch, Shilpa
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221603/
https://ncbi.nlm.nih.gov/pubmed/27786595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1232233
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