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Cocaine-mediated downregulation of miR-124 activates microglia by targeting KLF4 and TLR4 signaling
Cocaine is known to activate microglia both in vitro and in vivo. High expression of microglial Toll-like receptors (TLRs) and their downstream signal transducers play critical roles in determining microglial activation status. Emerging reports have also demonstrated that cocaine can enhance the str...
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| Udgivet i: | Mol Neurobiol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673594/ https://ncbi.nlm.nih.gov/pubmed/28478506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0584-5 |
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