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Cocaine-mediated downregulation of miR-124 activates microglia by targeting KLF4 and TLR4 signaling

Cocaine is known to activate microglia both in vitro and in vivo. High expression of microglial Toll-like receptors (TLRs) and their downstream signal transducers play critical roles in determining microglial activation status. Emerging reports have also demonstrated that cocaine can enhance the str...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Periyasamy, Palsamy, Liao, Ke, Kook, Yeon Hee, Niu, Fang, Callen, Shannon E., Guo, Ming-Lei, Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673594/
https://ncbi.nlm.nih.gov/pubmed/28478506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0584-5
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