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GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe
Microtubules are dynamic polymers of αβ-tubulin that have essential roles in chromosome segregation and organization of the cytoplasm. Catastrophe—the switch from growing to shrinking—occurs when a microtubule loses its stabilizing GTP cap. Recent evidence indicates that the nucleotide on the microt...
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| I publikationen: | Mol Biol Cell |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The American Society for Cell Biology
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5221584/ https://ncbi.nlm.nih.gov/pubmed/27146111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0199 |
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