Effects of anchor structure and glycosylation of Fcγ receptor III on ligand binding affinity

Isoforms of the Fcγ receptor III (FcγRIII or CD16) are cell surface receptors for the Fc portion of IgG and important regulators of humoral immune responses. Different ligand binding kinetics of FcγRIII isoforms are obtained in three dimensions by surface plasmon resonance and in two dimensions by a...

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Udgivet i:Mol Biol Cell
Main Authors: Jiang, Ning, Chen, Wei, Jothikumar, Prithiviraj, Patel, Jaina M., Shashidharamurthy, Rangaiah, Selvaraj, Periasamy, Zhu, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221579/
https://ncbi.nlm.nih.gov/pubmed/27582391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0470
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