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Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes Is Prevented with Decoy FcγReceptors

Autoimmune vasculitis is an endothelial inflammatory disease that results from the deposition of immune-complexes (ICs) in blood vessels. The interaction between Fcgamma receptors (FcγRs) expressed on inflammatory cells with ICs is known to cause blood vessel damage. Hence, blocking the interaction...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mula, Ramanjaneya V. R., Machiah, Deepa, Holland, Lauren, Wang, Xinyu, Parihar, Harish, Sharma, Avadhesh C., Selvaraj, Periasamy, Shashidharamurthy, Rangaiah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839578/
https://ncbi.nlm.nih.gov/pubmed/27101012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153620
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