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Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion
OBJECTIVE: Histone deacetylases are epigenetic regulators known to control gene transcription in various tissues. A member of this family, histone deacetylase 3 (HDAC3), has been shown to regulate metabolic genes. Cell culture studies with HDAC-specific inhibitors and siRNA suggest that HDAC3 plays...
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| Wydane w: | Mol Metab |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5220396/ https://ncbi.nlm.nih.gov/pubmed/28123935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.11.007 |
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