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Integrative regulation of physiology by histone deacetylase 3
Cell-type-specific gene expression is physiologically modulated by the binding of transcription factors to genomic enhancer sequences, to which chromatin modifiers such as histone deacetylases (HDACs) are recruited. Drugs that inhibit HDACs are in clinical use but lack specificity. HDAC3 is a stoich...
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| I publikationen: | Nat Rev Mol Cell Biol |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347506/ https://ncbi.nlm.nih.gov/pubmed/30390028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-018-0076-0 |
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