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Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces

Formins are large multidomain proteins required for assembly of actin cables that contribute to the polarity and division of animal and fungal cells. Formin homology-1 (FH1) domains bind profilin, and highly conserved FH2 domains nucleate actin filaments. We characterized the effects of two formins,...

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Autori principali: Kovar, David R., Pollard, Thomas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC522035/
https://ncbi.nlm.nih.gov/pubmed/15377785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405902101
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