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Model of Formin-Associated Actin Filament Elongation

Formin FH2 domains associate processively with actin-filament barbed ends and modify their rate of growth. We modeled how the elongation rate depends on the concentrations of profilin and actin for four different formins. We assume that (1) FH2 domains are in rapid equilibrium among conformations th...

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Main Authors: Vavylonis, Dimitrios, Kovar, David R., O’Shaughnessy, Ben, Pollard, Thomas D.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716371/
https://ncbi.nlm.nih.gov/pubmed/16483928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.01.016
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