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Model of Formin-Associated Actin Filament Elongation

Formin FH2 domains associate processively with actin-filament barbed ends and modify their rate of growth. We modeled how the elongation rate depends on the concentrations of profilin and actin for four different formins. We assume that (1) FH2 domains are in rapid equilibrium among conformations th...

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Bibliografiske detaljer
Main Authors: Vavylonis, Dimitrios, Kovar, David R., O’Shaughnessy, Ben, Pollard, Thomas D.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716371/
https://ncbi.nlm.nih.gov/pubmed/16483928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.01.016
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