De novo design of conformationally flexible transmembrane peptides driving membrane fusion

Fusion of biological membranes is mediated by distinct integral membrane proteins, e.g., soluble N-ethylmaleimide-sensitive factor attachment protein receptors and viral fusion proteins. Previous work has indicated that the transmembrane segments (TMSs) of such integral membrane proteins play an imp...

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Detalhes bibliográficos
Main Authors: Hofmann, Mathias W., Weise, Katrin, Ollesch, Julian, Agrawal, Prashant, Stalz, Holger, Stelzer, Walter, Hulsbergen, Frans, de Groot, Huub, Gerwert, Klaus, Reed, Jennifer, Langosch, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522031/
https://ncbi.nlm.nih.gov/pubmed/15456911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405175101
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