Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

The hypothalamic arcuate nucleus (ARC) is a major integration center for energy and glucose homeostasis that responds to leptin. Resistance to leptin in the ARC is an important component of the development of obesity and type 2 diabetes. Recently, we showed that Endospanin1 (Endo1) is a negative reg...

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Vydáno v:Mol Metab
Hlavní autoři: Vauthier, Virginie, Roujeau, Clara, Chen, Patty, Sarkis, Chamsy, Migrenne, Stéphanie, Hosoi, Toru, Ozawa, Koichiro, Rouillé, Yves, Foretz, Marc, Mallet, Jacques, Launay, Jean-Marie, Magnan, Christophe, Jockers, Ralf, Dam, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220283/
https://ncbi.nlm.nih.gov/pubmed/28123946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.10.009
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