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New Pharmacological Perspectives for the Leptin Receptor in the Treatment of Obesity

After its discovery in 1994, leptin became the great hope as an anti-obesity treatment based on its ability to reduce food intake and increase energy expenditure. However, treating obese people with exogenous leptin was unsuccessful in most cases since most of them present already high circulating l...

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Autori principali: Roujeau, Clara, Jockers, Ralf, Dam, Julie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195360/
https://ncbi.nlm.nih.gov/pubmed/25352831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00167
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