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Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity

OBJECTIVE: Dietary obesity is usually linked with hypothalamic leptin resistance, in which the primary impact is an interference in the homeostatic control of body weight and appetite. Notably, proanthocyanidins (PACs), which are the most abundant phenolic compounds present in human diet, modulate a...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Ibars, M, Ardid-Ruiz, A, Suárez, M, Muguerza, B, Bladé, C, Aragonès, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220160/
https://ncbi.nlm.nih.gov/pubmed/27677620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2016.169
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