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Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity

OBJECTIVE: Dietary obesity is usually linked with hypothalamic leptin resistance, in which the primary impact is an interference in the homeostatic control of body weight and appetite. Notably, proanthocyanidins (PACs), which are the most abundant phenolic compounds present in human diet, modulate a...

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Pubblicato in:Int J Obes (Lond)
Autori principali: Ibars, M, Ardid-Ruiz, A, Suárez, M, Muguerza, B, Bladé, C, Aragonès, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220160/
https://ncbi.nlm.nih.gov/pubmed/27677620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2016.169
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