Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling

BACKGROUND: Methyl-CpG-binding domain 3 (MBD3) is an aberrant expression in human malignancies. However, the role of MBD3 in pancreatic cancer progression remains to be clarified. In this study, we investigated the effects of MBD3 on the epithelial–mesenchymal transition (EMT), and the underlying me...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Xu, Min, He, Junbo, Li, Jie, Feng, Wen, Zhou, Hailang, Wei, Hong, Zhou, Meng, Lu, Ying, Zeng, Jian, Peng, Wanxin, Du, Fengyi, Gong, Aihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220156/
https://ncbi.nlm.nih.gov/pubmed/27898661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.397
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