Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling

BACKGROUND: Methyl-CpG-binding domain 3 (MBD3) is an aberrant expression in human malignancies. However, the role of MBD3 in pancreatic cancer progression remains to be clarified. In this study, we investigated the effects of MBD3 on the epithelial–mesenchymal transition (EMT), and the underlying me...

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Publicat a:Br J Cancer
Autors principals: Xu, Min, He, Junbo, Li, Jie, Feng, Wen, Zhou, Hailang, Wei, Hong, Zhou, Meng, Lu, Ying, Zeng, Jian, Peng, Wanxin, Du, Fengyi, Gong, Aihua
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220156/
https://ncbi.nlm.nih.gov/pubmed/27898661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.397
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