Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

To address the poor prognosis of mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia (iALL), we generated a panel of cell lines from primary patient samples and investigated cytotoxic responses to contemporary and novel Food and Drug Administration-approved chemotherapeutics....

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Veröffentlicht in:Leukemia
Hauptverfasser: Cruickshank, M N, Ford, J, Cheung, L C, Heng, J, Singh, S, Wells, J, Failes, T W, Arndt, G M, Smithers, N, Prinjha, R K, Anderson, D, Carter, K W, Gout, A M, Lassmann, T, O'Reilly, J, Cole, C H, Kotecha, R S, Kees, U R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220136/
https://ncbi.nlm.nih.gov/pubmed/27443263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.165
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