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A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation

The F-box proteins were originally identified as the key component of SKP1-Cullin1-F-box E3 ligase complexes that control the stability of their specific downstream substrates essential for cell growth and survival. However, the involvement of these proteins in type I IFN (IFN-I) signaling during in...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Peng, Di, Wang, Zining, Huang, Anfei, Zhao, Yong, Qin, F. Xiao-Feng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AAI 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220122/
https://ncbi.nlm.nih.gov/pubmed/27956528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601009
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